Archives: Content

These weblinks provide additional detail and references to the information contained in Chapter 43. The journal articles focus on the diagnosis and treatment options for osteomyelitis, fracture-related infection and prosthetic joint infection. The guidelines offer consensus views from expert panels convened specifically to study aspects of bone and joint infections. Journal articles https://www.sciencedirect.com/science/article/abs/pii/S0163445319302166?via%3Dihub/ (paid) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470655/ […]

Journal articles https://journals.lww.com/spinejournal/Abstract/1983/11000/The_Three_Column_Spine_and_Its_Significance_in_the.3.aspx/ (paid) This paper details the three-column classification of spinal trauma. First described by Denis for thoracolumbar fractures, it is still commonly used in surgical practice to predict if a spinal fracture is stable or unstable. The classification is applicable for spinal fractures from C3 to L5 (not just thoracolumbar fractures). https://journals.lww.com/spinejournal/Fulltext/2010/10011/Early_Versus_Late_Stabilization_of_the_Spine_in.6.aspx/ (free) […]

Journal articles/Full editions Oesophageal Atresia/Tracheoesophageal Fistula https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0039-1693116/ (paid) Expert consensus exercise in the management of oesophageal atresia. https://doi.org/10.1038/s41572-019-0077-0/ (paid) Comprehensive review article on oesophageal atresia/tracheoesophageal fistula. Intestinal Atresias https://www.sciencedirect.com/science/article/abs/pii/S1055858622000014/ (paid) Overview article of duodenal obstruction. https://fn.bmj.com/content/fetalneonatal/early/2019/06/22/archdischild-2019-317085.full.pdf (free) Population-based cohort study exploring management and outcomes of infants born with duodenal atresia. Malrotation and Volvulus https://www.sciencedirect.com/science/article/abs/pii/S1055858622000026/ (paid) […]

Journal articles https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.119.313574?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed/ (free) Review article on the use of heart transplantation and durable ventricular assist devices in the treatment of advanced heart failure. https://journals.lww.com/co-transplantation/Abstract/2021/02000/Heart_transplantation_candidacy.11.aspx/ (paid) Review of the selection of patients for heart transplantation and the effects of urgent/priority allocation systems. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435913/ (free) Review of the current status of lung transplantation and future developments […]

Guideline https://www.england.nhs.uk/wp-content/uploads/2018/12/Small-bowel-transplantation-service-adults.pdf/ A useful site setting out the commissioning requirements of a service. Report https://nhsbtdbe.blob.core.windows.net/umbraco-assets-corp/19865/nhsbt-annual-report-on-intestine-transplantation-201920.pdf/ The 2020 annual report on intestine transplantation.

Journal article https://www.bmj.com/content/357/bmj.j1321/ (paid) This is a comprehensive review of pancreas transplantation published in BMJ in 2017. It describes the current state of pancreas transplantation, gaps in knowledge and future studies needed to enable more patients to benefit from this treatment Websites https://www.odt.nhs.uk/transplantation/pancreas/ This is a link to the pancreas transplant page on the Organ […]

Guidelines https://www.bsg.org.uk/clinical-resource/adult-liver-transplantation-a-uk-clinical-guideline/ (free) Two guidelines from the British Society of Gastroenterology giving information on the various indications of liver transplant, process of assessment of a liver transplant patient, surgical aspects and postoperative complications and outcomes. https://nhsbtdbe.blob.core.windows.net/umbraco-assets-corp/22847/pol195.pdf/ (free) Policy document on the selection of adult and paediatric patients for liver transplant and the principles of organ […]

Websites www.odt.nhs.uk/statistics-and-reports/ This website contains details of the annual activity and outcomes of all solid organ transplantation in the UK. https://odt.btru.nihr.ac.uk/ This is the website of the NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation. The unit conducts some of the leading transplant research in the UK. https://www.edqm.eu/en/-/newsletter-transplant-2021-now-available/ Summary of comprehensive information […]

Guidelines https://www.gov.uk/guidance/cervical-screening-programme-overview/ (free) Information on the NHS Cervical Screening Programme, including the target population and screening tests. https://www.eshre.eu/Guidelines-and-Legal/%20Guidelines/Endometriosis-guideline.aspx/ (free) Best practice advice on the management of women with endometriosis, including recommendations on the diagnostic approach and treatments for the relief of symptoms and management of infertility. https://www.nice.org.uk/guidance/ng126/resources/ectopic-pregnancy-and-miscarriage-diagnosis-and-initial-management-pdf-66141662244037/ (free) National Institute for Health and Care Excellence […]

Journal articles https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD000479.pub6/full/ (free) A Cochrane systematic review evaluating the effect of varicocele treatment on live birth and pregnancy rate in subfertile couples where the male has a varicocele. Despite the heterogeneity of data, there is an increase in successful outcomes after treating clinical varicoceles. https://static1.squarespace.com/static/5c4498eeaa49a13f3137ee64/t/5c6c11bb085229f28786151c/1550586300939/Kulkarni+Sperm+retrieval+in+KS.pdf/ (free) Link to an e-learning module on the impact […]

Journal articles https://bjui-journals.onlinelibrary.wiley.com/doi/epdf/10.1046/j.1464-410X.1996.23121.x/ (paid) The first described dorsal onlay buccal graft urethroplasty, which is one of the most commonly performed approaches. https://www.sciencedirect.com/science/article/abs/pii/S0090429501013772?via%3Dihub/ (paid) Asopa’s ventral inlay approach, which is vascular preserving. https://www.sciencedirect.com/science/article/abs/pii/S0090429596001549?via%3Dihub/ (paid) Evaluation of the efficacy of buccal mucosa in the repair of adult urethral stricture disease. https://www.auajournals.org/doi/full/10.1016/j.juro.2012.05.020/ (paid) The Kulkarni technique, which is […]

Journal articles https://www.nejm.org/doi/full/10.1056/nejmoa030656/ (free) Medical Therapy of Prostatic Symptoms (MTOPS) trial. This is a most important trial on medical management of prostate cancer. https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(14)70361-4/fulltext/ (free) Prostate testing for cancer and treatment (ProtecT) trial. This is a landmark trial that discusses the outcome of active surveillance versus curative treatment. https://www.nejm.org/doi/full/10.1056/nejmoa1801993/ (free) Prostate Evaluation for Clinically Important […]

Journal articles https://onlinelibrary.wiley.com/doi/epdf/10.1002/nau.20870/ (free) Expert panel recommendations from the International Consultation on Incontinence on the definitions, evaluation and treatment of urinary incontinence. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897743/ (free) Excellent review summarising the entire neural control of micturition. Guidelines https://uroweb.org/guideline/urological-infections/ (free) European Association of Urology guidelines on urological infections, providing an up-to-date evidence-based review of the management of all urological […]

Journal articles https://www.sciencedirect.com/science/article/abs/pii/S0302283819306141/ (paid) Medical expulsive therapy with selective a-blockers is recommended for distal ureteric stones between 5 and 10 mm as the initial modality. The quality of evidence for this recommendation is low. https://www.auajournals.org/doi/abs/10.1016/j.juro.2016.09.160/ (paid) Bosniak classification of renal cysts. The original Bosniak classification was proposed in 1986. It has been subsequently modified to be […]

Journal articles https://www.nejm.org/doi/full/10.1056/nejm199104253241702/ (free) This is one of the first publications on the use of prostate-specific antigen (PSA) for screening for prostate cancer and is a landmark study as it helped establish population screening with PSA. https://www.sciencedirect.com/science/article/abs/pii/S009042959600091X?via%3Dihub/ (paid) This study helped analyse differences in prostate-specific antigen at different ages and thus suggested that there may […]

Journal articles https://jnccn.org/view/journals/jnccn/15/5S/article-p726.xml/ (free) Human papillomavirus and the challenges and opportunities in relation to cervical, vaginal and anal cancers. https://onlinelibrary.wiley.com/doi/10.1111/j.1463-1318.2008.01681.x/ (free) Association of Coloproctology of Great Britain and Ireland (ACPGBI) position statement for the management of anal fissure, informing aetiology, diagnosis and management of this condition. https://onlinelibrary.wiley.com/doi/full/10.1111/j.1463-1318.2007.01372.x/ (paid) Association of Coloproctology of Great Britain and […]

Journal articles https://ascopubs.org/doi/full/10.1200/JCO.2006.09.7840/ (paid) This review article summarises the latest information about organ preservation for rectal cancer. Controversies around organ preservation and the expected outcomes are discussed along with the need for strict guidelines for patient selection. https://www.sciencedirect.com/science/article/abs/pii/S0009926019301680?via%3Dihub/ (paid) This review article discusses the rationale for magnetic resonance imaging (MRI) staging for advanced rectal cancer, […]

Journal articles https://www.sciencedirect.com/science/article/abs/pii/S1072751505011361?via%3Dihub/ (paid) Influence of time on risk of bowel resection in complete small bowel obstruction. https://www.sciencedirect.com/science/article/abs/pii/S0002961015004249?via%3Dihub/ (paid) Water-soluble contrast agent in adhesive small bowel obstruction: a systematic review and meta-analysis of diagnostic and therapeutic value. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1356393/ (free) Long-term prognosis after operation for adhesive small bowel obstruction. https://onlinelibrary.wiley.com/doi/full/10.1111/j.1463-1318.2007.01371.x/ (paid) The management of malignant large […]

Journal article https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443846/ (free) A review of the current standard treatment, evolving treatment paradigms and the emerging biomarkers that are likely to help improve patient selection and personalisation of therapy, leading to superior outcomes for patients with early-stage colon cancer. Guidelines https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774998/ (free) UK guidelines providing comprehensive clinical guidance on the management of patients with […]

Journal articles https://www.sciencedirect.com/science/article/abs/pii/S0748798316300294?via%3Dihub/ (paid) Early and long-term outcomes from the Basingstoke experience of more than 1000 patients who underwent cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) for pseudomyxoma peritonei. https://journals.lww.com/ajsp/Abstract/2016/01000/A_Consensus_for_Classification_and_Pathologic.4.aspx/ (paid) Consensus document outlining the pathological classification of appendix neoplasia and associated pseudomyxoma peritonei. https://www.sciencedirect.com/science/article/abs/pii/S0748798320301141?via%3Dihub/ (paid) Clinical practice guidelines for the diagnosis and management of […]

Journal articles https://www.nejm.org/doi/10.1056/NEJMra1907607?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed/ (free) A review of new treatments for inflammatory bowel disease, with a focus on clinical and endoscopic remission and precise molecular targeting of inflammatory cascades. https://www.sciencedirect.com/science/article/abs/pii/S0016508506025224?via%3Dihub/ (paid) This paper presents the results of the CHARM trial that evaluated the efficacy and safety of adalimumab in the maintenance of response and remission in […]

Journal article https://ascopubs.org/doi/full/10.1200/jop.18.00135/ Excellent review of the management of small bowel neuroendocrine tumours. Guidelines https://fascrs.org/ascrs/media/files/downloads/Clinical%20Practice%20Guidelines/clinical_practice_guidelines_for_ostomy_surgery.pdf/ Guidelines from the American Society of Colon and Rectal Surgeons surrounding stoma formation and management. https://www.bhiva.org/file/5f4625b5b191b/OI-guidelines-gastrointestinal.pdf/ Guidelines on the diagnosis and management of gastrointestinal tract infections in patients with human immunodeficiency virus.

Journal articles https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001845/ (free) This very detailed review tells you everything you might ever need to know about irritable bowel syndrome. https://www.nature.com/articles/nrgastro.2012.134/ (paid) This very detailed review covers the pathophysiology and management of postoperative ileus. https://pubmed.ncbi.nlm.nih.gov/33263938/ (free) This open access review published in 2021 summarises the current understanding of the epidemiology, pathophysiology and diagnosis of […]

Journal articles https://www.sciencedirect.com/science/article/abs/pii/S0140673610618521?via%3Dihub/ (paid) A review article covering all aspects of chronic pancreatitis. https://www.nejm.org/doi/full/10.1056/NEJMoa1809775/ (free) A major step forward in defining the new regimens for adjuvant therapy in pancreatic cancer. https://www.sciencedirect.com/science/article/abs/pii/S0140673620309740?via%3Dihub/ (paid) Another major step forward in defining the new regimens for adjuvant therapy in pancreatic cancer. Guidelines https://wjes.biomedcentral.com/articles/10.1186/s13017-019-0247-0/ (free) Current guidelines on the management […]